Blockbuster may refer to:
TV and entertainment-
Blockbuster (entertainment), any very successful movie, theatrical play, etc.
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Blockbuster LLC, a video and game rental chain
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Blockbusters (U.S. game show), an American game show which had two separate runs in the 1980s
Comics-
Blockbuster (DC Comics), the name of four DC Comics characters
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Blockbuster (Man-Brute), a Marvel Comics character introduced in 1970
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Blockbuster (Marauder), a Marvel Comics character introduced in 1986
Military
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Blockbuster bomb, a series of WWII-era air dropped bombs large enough to demolish a city block
- "Operation
Blockbuster", a Anglo-Canadian military operation in the Netherlands during World War II
Other
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Blockbuster (book), by Tom Shone
- A
blockbuster drug, a drug generating more than $1 billion of revenue for its owner each year
- A
block buster, a splitting maul, a type of axe